As the Cannabis market grows for both medical and recreational use, so does the requirement for standardized quality control within the industry. In terms of Cannabis quality control there are numerous things to consider, from moisture content to pesticide use.
Moisture Content – Cannabis flower moisture content should be tested and controlled to: minimize the potential risk of mold formation; control microbiological levels; ensure proper drying, curing and storage conditions; and support product shelf life. Some manufacturing processes for cannabis quality assurance plan also demand a certain water content in the starting material.
Terpenoids and Cannabinoids Analysis
The level of terpenoids and cannabinoids within the starting material determines the most appropriate industrial processing method and which final cannabis product is going to be manufactured. This analysis is generally completed using LC-MS (Liquid Chromatography Mass Spectrometry) or GC (Gas Chromatography). LC-MS and GC demand a flow of inert gas including hydrogen or nitrogen, both of which can easily be supplied by way of a gas generator. Discover more regarding the Peak Scientific selection of gas generators for GC & LC-MS here.
Pesticides and Herbicides – As with other agricultural crops and products intended for human consumption, Cannabis plants needs to be tested for herbicides and pesticides. Detecting pesticides and herbicides can be difficult because of the complexity of cannabis material. GCMS (Gas Chromatography Mass Spectrometry) is usually used for this specific purpose.
Microbiological Screening – Medical Cannabis is usually employed for HIV and cancer patients in which the patient’s immunity mechanism has become compromised. Therefore, high microbial levels or pathogenic micro-organisms could be deadly. It is necessary then that several Mycotoxins and fungus types should be detected included in cannabis quality control and release specifications.
Residual Solvents – Where solvents have been used included in Cannabis product processing, solvent residuals in the final products needs to be tested to ensure they meet the accepted criteria. The FDA has published zvqtob criteria for residual solvents in APIs for pharmaceutical use.
Chemical Toxins – Like various other plants, Cannabis draws metals from your earth. It really is therfore required to test for Mercury, Lead, Arsen and Cadmium.
Cannabinoid Concentration – Concentration ranges for cannabinoids like THC,THCa, CBD, CBDa, CBN, CBC, CBG should match the ranges specified on the product label, based on product usage purpose, patient’s condition, age etc. Cannabinoid concentrations could be tested using LC-MS (Liquid Chromatography Mass Spectrometry) and HPLC (High Performance Liquid Chromatography) . You will find an array of Peak Scientific nitrogen gas generators designed particularly for LC-MS, available here.
Terpene Concentration – Terpenes increase cannabinoids’ therapeutic effects and are recognized to have their own health benefits, additionally they play a role in Cannabis taste and aroma. They can be detected using GC.
Taking the above into consideration, it is actually clear that there is a necessity for standarized procedures for all the Cannabis analysis and testing process so that you can guarantee safe use. The safest method to supply cannabis testing laboratories with gas for his or her LC-MS and GC is via gas generators, which do not present the health and safety risks associated with gas cylinders.